方法1：

import ctypes
import os
import platform
import sys
def get_free_space_mb(folder):
  """ Return folder/drive free space (in bytes)
  """
  if platform.system() == 'Windows':
    free_bytes = ctypes.c_ulonglong(0)
    ctypes.windll.kernel32.GetDiskFreeSpaceExW(ctypes.c_wchar_p(folder), None, None, ctypes.pointer(free_bytes))
    return free_bytes.value/1024/1024/1024 
  else:
    st = os.statvfs(folder)
    return st.f_bavail * st.f_frsize/1024/1024
print(get_free_space_mb('C:\\'),'GB')

方法2：

import win32com.client as com
def TotalSize(drive):
  """ Return the TotalSize of a shared drive [GB]"""
  try:
    fso = com.Dispatch("Scripting.FileSystemObject")
    drv = fso.GetDrive(drive)
    return drv.TotalSize/2**30
  except:
    return 0
def FreeSpace(drive):
  """ Return the FreeSpace of a shared drive [GB]"""
  try:
    fso = com.Dispatch("Scripting.FileSystemObject")
    drv = fso.GetDrive(drive)
    return drv.FreeSpace/2**30
  except:
    return 0
workstations = ['dolphins']
print ('Hard drive sizes:')
for compName in workstations:
  drive = '\\\\' + compName + '\\c$'
  print ('*************************************************\n')
  print (compName)
  print ('TotalSize of %s = %f GB' % (drive, TotalSize(drive)))
  print ('FreeSpace on %s = %f GB' % (drive, FreeSpace(drive)))
  print ('*************************************************\n')

运行效果如下图：